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Related Experiment Videos

Phenol: tissue distribution in a fatality.

C Lo Dico1, Y H Caplan, B Levine

  • 1Office of the Chief Medical Examiner, Baltimore, MD.

Journal of Forensic Sciences
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

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Phenol ingestion can be fatal, as seen in a case involving a 40-year-old female. Postmortem analysis revealed high phenol concentrations in various tissues, highlighting its toxicity.

Area of Science:

  • Forensic Toxicology
  • Clinical Chemistry

Background:

  • Phenol, a common disinfectant, is highly toxic when ingested.
  • Accidental or intentional ingestion of phenol can lead to severe poisoning.

Observation:

  • A case report details the fatal ingestion of phenol by a 40-year-old female.
  • Phenol concentrations were measured in blood, urine, bile, and multiple organs.

Findings:

  • Blood phenol level was 130 mg/L, with higher concentrations in the brain (486 mg/kg) and stomach content (668 mg).
  • Elevated phenol levels were also found in kidney (331 mg/kg), liver (228 mg/kg), muscle (204 mg/kg), and bile (187 mg/L).
  • These findings were compared with existing literature data on phenol toxicity.

Implications:

Related Experiment Videos

  • This case underscores the lethal potential of phenol ingestion.
  • Accurate toxicological analysis is crucial for determining cause of death in phenol poisoning cases.
  • Understanding tissue distribution aids in interpreting postmortem findings.