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Acid Activation in Phenyliodine Dicarboxylates: Direct Observation, Structures, and Implications

Susana Izquierdo1, Stéphanie Essafi2, Iker Del Rosal2

  • 1Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology , 43007, Tarragona, Spain.

Journal of the American Chemical Society
|September 9, 2016
PubMed
Summary

Hypervalent iodine reagents, crucial for organic synthesis, are activated by acids. This study elucidates the mechanism of this activation using PhI(OAc)2 and BF3·Et2O, revealing structural and electronic insights into enhanced reactivity.

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