Related Experiment Video

Updated: Mar 15, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

15.2K

Factors Affecting Adherence to Statins in Hypercholesterolemic Kuwaiti Patients: A Cross-Sectional Study

Meisa Al-Foraih1, Shawn Somerset

  • 1Public Authority for Applied Education and Training, Safat, Kuwait.

Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre
|September 9, 2016
PubMed

Insights

Kuwaiti hypercholesterolemic patients show low statin adherence, particularly younger individuals. Poor adherence is linked to higher coronary heart disease risk factors like elevated cholesterol.

Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Background:

  • Hypercholesterolemia is a significant risk factor for coronary heart disease (CHD).
  • Statin therapy is crucial for managing hypercholesterolemia and reducing CHD risk.
  • Understanding adherence patterns is vital for effective cardiovascular disease prevention strategies.

Purpose of the Study:

  • To assess statin adherence rates among hypercholesterolemic patients in Kuwait.
  • To identify demographic and clinical factors associated with poor statin adherence.
  • To investigate the relationship between statin adherence and coronary heart disease (CHD) risk profile.

Main Methods:

  • A cross-sectional study involving 200 hypercholesterolemic patients aged 30-69 years.
  • Statin adherence was measured using the Morisky Medication Adherence Scale.
  • Data on demographics, medical history, and risk factors were collected via interviews and laboratory tests.

Main Results:

  • A high prevalence of low statin adherence (58.5%) was observed; no patients achieved high adherence.
  • Younger patients (30-50 years) and those without diabetes exhibited lower adherence.
  • Low statin adherence correlated with increased plasma cholesterol and low-density lipoprotein levels.

Conclusions:

  • Low statin adherence is prevalent in Kuwaiti hypercholesterolemic patients, especially younger individuals.
  • Factors such as age and diabetes status influence adherence.
  • Reduced statin adherence is associated with an unfavorable coronary heart disease risk profile.
Abstract

More Related Videos

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring08:45

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring

Published on: November 17, 2018

14.2K
Cholesterol Efflux Assay07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

30.8K

Related Concept Videos

Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
1.7K
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
562
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...
2.5K
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
1.8K
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
798
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
745