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Related Concept Videos

Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

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Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.4K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Remote Laboratory Management: Respiratory Virus Diagnostics
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Remote Laboratory Management: Respiratory Virus Diagnostics

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[Update in Infectious Diseases 2016].

F J Candel1, A B García-García, M Peñuelas

  • 1Francisco Javier Candel González. Servicio de Microbiología Clínica. Hospital Clínico San Carlos. Universidad Complutense. Madrid. Avda Doctor Martín Lágos s/n28040 Madrid, Spain. fj.candel@gmail.com.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|September 9, 2016
PubMed
Summary
This summary is machine-generated.

Antimicrobial resistance poses significant health and economic challenges. This 2016 update reviews strategies for combating multi-resistant bacteria and fungal infections, including novel therapies and pediatric considerations.

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Area of Science:

  • Microbiology
  • Epidemiology
  • Clinical Medicine
  • Pharmacology
  • Mycology
  • Parasitology

Background:

  • Antimicrobial resistance (AMR) presents escalating global health, social, and economic burdens.
  • Numerous initiatives are underway to mitigate the impact of resistance across all governmental levels.
  • The 2016 update focuses on multi-drug resistant bacteria and challenging fungal and parasitic infections.

Purpose of the Study:

  • To provide a comprehensive overview of multi-resistant bacteria, covering microbiological, epidemiological, and clinical facets.
  • To explore therapeutic strategies for bacterial infections, from historical drugs to modern combinations and stewardship programs.
  • To analyze clinical scenarios of fungal infections, including yeast and filamentous fungi, with a focus on pediatric versus adult invasive infections.
  • To review treatments for severe or drug-resistant malaria.

Main Methods:

  • Review of microbiological, epidemiological, and clinical data on multi-resistant bacteria.
  • Analysis of therapeutic resources, including drug combinations and antimicrobial stewardship programs.
  • Examination of clinical cases involving various fungal species and patient populations.
  • Literature review of treatment protocols for severe and resistant malaria.

Main Results:

  • Identification of key aspects of multi-resistant bacteria and their management.
  • Evaluation of diverse therapeutic options for bacterial and fungal infections.
  • Comparison of invasive fungal infections in pediatric and adult populations.
  • Assessment of current treatment approaches for drug-resistant malaria.

Conclusions:

  • Effective containment of antimicrobial resistance requires a multifaceted approach integrating microbiological, clinical, and therapeutic strategies.
  • Antimicrobial stewardship programs are crucial for optimizing treatment and combating resistance.
  • Understanding specific challenges in pediatric populations is vital for treating invasive fungal infections.
  • Addressing drug-resistant malaria remains a critical public health priority.