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Updated: Mar 15, 2026

Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper
Published on: February 27, 2021
Chitosan: An efficient biomacromolecule support for synergic catalyzing of Hantzsch esters by CuSO4
Mohammad G Dekamin1, Elham Kazemi1, Zahra Karimi1
1Pharmaceutical and Biologically-Active Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.
Abstract:
The synergic effect of the chitosan biomacromolecule support for catalyzing of Hantzsch esters formation by CuSO4 has been demonstrated for one-pot and efficient pseudo-four-component reaction to afford a wide range of 1,4-dihydropyridine (DHP) or polyhydroquinoline (PHQ) derivatives. The desired products were simply prepared from different aldehydes, β-dicarbonyls and ammonium acetate in the presence of a low loading of chitosan supported copper(II) sulfate (CSCS) in EtOH under reflux conditions. The biodegradable CSCS catalyst was characterized by field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray spectroscopy analysis (EDX) methods as well as coupled plasma-atomic emission (ICP-AE) and FT-IR spectroscopy. The CSCS catalyst is recyclable and reused four times without significant loss of its activity.
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