Related Experiment Video
Updated: Mar 15, 2026
Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method
Published on: July 4, 2021
[Establishment of traumatic occlusion model in Sprague-Dawley rats]
Xian-Zhen Xin1, Xu Yang, Bin Wei
1Department of Prosthodontics,Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China.
Purpose:
In this study, different methods were used to observe and obtain the most effective one to establish occlusal trauma model in Sprague-Dawley rats.
Methods:
SPF male SD rats weighing 150~200 g and aged 10 to 12 weeks were used in this study. The rats' maxillary molars were bonded with stainless steel wire, resin , casting half crown , casting half combined crowns, half crown using selective laser melting (SLM) technology, half combined crowns using SLM technology through Super-bond and Multi-link bonding under general anesthesia. After bonding, the experimental device expulsion rates were observed daily. The data was analyzed statistically using Fisher's exact test with SAS 8.2 software package.
Results:
There was no significant difference between the falling rates of using super-bond and using multi-link. Under the situation in which different bonding methods exerted no influence on the falling rates, there was significant difference between different experimental devices (P<0.0001).
Conclusions:
The restorations fabricated with SLM technology is valid and feasible to induce occlusal point in building occlusal trama model using SD rats.
