New mathematical modelling of blood lactate kinetics during ramp mode exercise in man

The lactate (LA) kinetics of the whole body in exercise was described using the two-compartment model in consideration of the underlying physiological mechanism, and LA kinetics during the ramp mode exercise was analyzed. The estimated pattern of the glycolytic energy supply showed the progressive increase concurrently with the onset of ramp mode exercise and this pattern was just like a ramp phenomenon. Based on this result, it is proposed that blood LA kinetics during ramp exercise should be described mathematically as a continuous model, called "2nd-order model."