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Updated: Mar 15, 2026

Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis
Published on: January 2, 2017
Modern management of phagocyte defects
Lorenza Lisa Serena Lanini1, Seraina Prader1, Ulrich Siler1
1Division of Immunology, University Children's Hospital Zurich and Children's Research Centre, University Zurich, Switzerland.
Abstract:
Phagocytic neutrophil granulocytes are among the first immune cells active at sites of infection, forming an important first-line defense against invading microorganisms. Congenital immune defects concerning these phagocytes may be due to reduced neutrophil numbers or function. Management of affected patients depends on the type and severity of disease. Here, we provide an overview of causes and treatment of diseases associated with congenital neutropenia, as well as defects of the phagocytic respiratory burst.
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