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Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

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Updated: Mar 15, 2026

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Published on: April 7, 2023

Skin compatibility and antimicrobial studies on biofunctionalized polypropylene fabric.

Sadiya Anjum¹, Amlan Gupta², Deepika Sharma²

¹Bioengineering Laboratory, Department of Textile Technology, Indian Institute of Technology, New Delhi 110016, India.

Materials Science & Engineering. C, Materials for Biological Applications

|September 11, 2016

Summary

This study developed antimicrobial fabric using nanosilver-loaded nanogels and essential oils on polypropylene fabric. The resulting material shows excellent antimicrobial activity and is safe for skin contact applications.

Keywords:

Antimicrobial Essential oil Inflammation Nanosilver nanogel Polyacrylamide Skin irritation

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Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

Area of Science:

Materials Science
Biotechnology
Textile Engineering

Background:

Antimicrobial fabrics are crucial for preventing infections in skin-contacting applications.
Developing safe and effective antimicrobial materials remains a significant challenge.
Nanosilver and essential oils offer potent antimicrobial properties.

Purpose of the Study:

To develop a novel antimicrobial fabric for skin-contacting applications.
To create nanosilver-loaded bioactive nanogels for fabric functionalization.
To evaluate the antimicrobial efficacy and biocompatibility of the developed fabric.

Main Methods:

Preparation of nanosilver-loaded polyacrylamide nanogels via gamma irradiation.
Combination of nanogels and essential oils using polyethylene glycol as a carrier.
Plasma functionalization of polypropylene fabric for bio-immobilization.
Coating the fabric with the bioactive emulsion and subsequent antimicrobial testing.
In vivo skin irritation and histopathology studies on Swiss albino mice.

Main Results:

Nanosilver nanogels with particle sizes of 10-50nm were successfully synthesized.
The biofunctionalized fabric demonstrated significant antimicrobial activity against Staphylococcus aureus and Escherichia coli.
Skin irritation studies showed no adverse inflammatory response.
Histopathology confirmed the material's biocompatibility for skin contact.

Conclusions:

The developed nanosilver-loaded bioactive fabric is a promising candidate for antimicrobial skin-contacting applications.
The combination of nanogels, essential oils, and plasma-treated fabric offers an effective strategy for antimicrobial material development.
The fabric exhibits excellent antimicrobial efficacy and a favorable safety profile.