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Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

Polyethylene/silver-nanofiber composites: A material for antibacterial films.

Paula A Zapata¹, Maialen Larrea², Laura Tamayo³

¹Grupo Polímeros, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Casilla 40, Correo 33, Santiago, Chile.

Materials Science & Engineering. C, Materials for Biological Applications

|September 11, 2016

Summary

Silver nanofibers incorporated into polyethylene nanocomposites demonstrate significant antibacterial properties against Escherichia coli. These silver-nanofiber composites effectively inhibit bacterial growth through membrane disruption, attributed to silver ion release.

Keywords:

Antibacterial properties Biomaterials In situ polymerization Nanocomposites Polyethylene Silver nanofibers

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High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

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Published on: November 5, 2016

Area of Science:

Materials Science
Nanotechnology
Polymer Science

Background:

Silver nanofibers (Ag-Nfbs) are synthesized via hydrothermal treatment.
Ag-Nfbs were incorporated into polyethylene (PE) at 3 and 5 wt% during in situ polymerization.
The study focuses on developing PE nanocomposites with antibacterial properties.

Purpose of the Study:

To synthesize and characterize silver-nanofiber/polyethylene (Ag-Nfbs/PE) nanocomposites.
To evaluate the antibacterial efficacy of these nanocomposites against Escherichia coli ATCC 25923.
To elucidate the mechanism behind the observed antibacterial activity.

Main Methods:

Hydrothermal synthesis of silver nanofibers (~80nm diameter).
In situ polymerization of PE with 3 and 5 wt% Ag-Nfbs.
Antibacterial evaluation using bacterial viability tests on Escherichia coli ATCC 25923 after 8h incubation.
Transmission Electron Microscopy (TEM) analysis to investigate the antibacterial mechanism.

Main Results:

PE nanocomposites containing 3 and 5 wt% Ag-Nfbs were successfully synthesized.
The Ag-Nfbs/PE nanocomposites inhibited Escherichia coli growth by 88% and 56%, respectively.
TEM analysis indicated that antibacterial activity is linked to bacterial membrane disruption, not morphological changes.

Conclusions:

Silver-nanofiber/polyethylene nanocomposites exhibit potent antibacterial activity against Escherichia coli.
The antibacterial effect is primarily due to the release of silver ions and subsequent disruption of bacterial cell membranes.
These findings highlight the potential of Ag-Nfbs/PE nanocomposites for applications requiring antimicrobial properties.