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Related Experiment Videos

Missing pulse steady-state free precession.

S Patz1, S T Wong, M S Roos

  • 1Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.

Magnetic Resonance in Medicine
|May 1, 1989
PubMed
Summary
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A novel fast imaging technique, missing pulse steady-state free precession (MP-SSFP), enhances signal-to-noise ratio and tissue contrast. This method offers improved field inhomogeneity resistance compared to conventional fast imaging techniques.

Area of Science:

  • Magnetic Resonance Imaging
  • Pulse Sequence Design
  • Medical Physics

Background:

  • Steady-state free precession (SSFP) techniques are widely used in fast magnetic resonance imaging.
  • Conventional SSFP methods are sensitive to magnetic field inhomogeneities, potentially limiting image quality.
  • Developing advanced SSFP sequences is crucial for improving imaging speed and robustness.

Purpose of the Study:

  • To introduce and characterize a novel fast imaging technique: missing pulse steady-state free precession (MP-SSFP).
  • To investigate the potential of MP-SSFP for optimizing signal-to-noise ratio and tissue contrast.
  • To evaluate the sensitivity of MP-SSFP to magnetic field inhomogeneities.

Main Methods:

  • MP-SSFP was implemented by omitting every third radiofrequency (RF) pulse in a standard SSFP sequence.

Related Experiment Videos

  • An analytical expression for signal strength was derived, considering flip angles, interpulse interval, and dephasing.
  • Two specific flip angle configurations (θ1 = θ2 and θ1 = -θ2) were analyzed to demonstrate contrast variations.

    • Main Results:

    • MP-SSFP generates a refocused echo that is less sensitive to field inhomogeneities than gradient-recalled echoes.
    • The derived analytical expression shows that flip angles (θ1, θ2) offer two degrees of freedom for optimization.
    • Different flip angle strategies yielded distinct tissue contrasts, with one case showing strong signals from short T1/T2 spins and another mimicking conventional SSFP contrast.

    Conclusions:

    • MP-SSFP is a promising fast imaging technique offering enhanced control over signal-to-noise ratio and tissue contrast.
    • The technique demonstrates improved robustness against magnetic field inhomogeneities.
    • Further experimental validation is suggested to explore the predicted multi-component signal behavior.