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Treatment of allergic children - Where is the progress (for the practicing allergist)?
A F Wert1, D Posa2, O Tsilochristou3
1Department of Paediatric Pneumology Allergy and Neonatology, Hannover Medical School, Hannover, Germany. wert.franziska@mh-hannover.de.
Insights
Pediatric asthma and allergic disease treatments are advancing, with new approaches emerging for children. This review covers recent progress and highlights promising therapies for the future.
Area of Science:
- Pediatric Allergy and Immunology
- Pediatric Therapeutics
- Allergic Disease Management
Background:
- Children require separate therapeutic considerations for allergic diseases compared to adults.
- Regulatory bodies mandate specific pediatric investigational plans for drug development.
- Recent years have seen significant advancements in treating pediatric allergic and immunologic disorders.
Purpose of the Study:
- To review recent progress in the treatment of pediatric asthma and allergic diseases.
- To highlight novel therapeutic approaches for allergic children.
- To provide an outlook on future treatment changes.
Main Methods:
- Literature review of publications from late 2013 to May 2016.
- Focus on studies addressing pediatric asthma and allergic diseases.
- Inclusion of research from the journal and beyond.
Main Results:
- Summarizes advancements in pediatric allergic disease treatment.
- Identifies promising novel therapeutic strategies.
- Highlights the evolving landscape of pediatric allergy care.
Conclusions:
- Progress in pediatric allergic disease treatment is notable.
- Novel therapies are expected to significantly impact future care for allergic children.
- Continued research is crucial for advancing pediatric allergy management.
Abstract:
For any kind of therapeutic intervention in allergic diseases such as environmental control, pharmacological, or immunomodulating treatment including educational programs, children are addressed separately from adults. Health authorities like the Food and Drug Administration in the United States of America or the European Medicine Agency in Europe request a specific 'Pediatric investigational plan' with studies addressing dose-response relationship, safety, and efficacy for infants, children, and adolescents. During the last 2 years, promising advances have been reported for the treatment of a variety of allergic and immunologic disorders. This review summarizes the progress in the treatment of pediatric asthma and allergic diseases, based on publications of approximately the last 2.5 years (end of 2013 until May 2016) in and beyond this journal. Meanwhile, it highlights areas with promising novel therapeutic approaches, which are likely to change treatment for allergic children in the near future.
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