Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 15, 2026

Potentiodynamic Corrosion Testing
08:43

Potentiodynamic Corrosion Testing

Published on: September 4, 2016

18.5K

[Are the cobalt hip prosthesis dangerous?].

Virginie Mistretta1, William Kurth2, Corinne Charlier1

  • 1Service de toxicologie clinique, médico-légale, de l'environnement et en entreprise, CHU Sart-Tilman, 1 avenue de l'Hôpital, 4000 Liège, Belgique.

Medecine Sciences : M/S
|September 13, 2016
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum PFAS levels measured in the general population of Kinshasa, Democratic Republic of Congo, in 2022-2023.

Environmental science and pollution research international·2026
Same author

[The first 1,000 days of life : a period of vulnerability to environmental pollutants].

Revue medicale de Liege·2026
Same author

Urinary concentration levels and health risk assessment of phthalates, parabens, benzophenone-3, bisphenols and triclosan in the adult population of Kinshasa: a cross-sectional study in Democratic Republic of Congo (DRC).

Archives of public health = Archives belges de sante publique·2026
Same author

Exposure of Belgian children to multiple classes of currently used pesticides.

The Science of the total environment·2026
Same author

Impact of antenatal exposure to a mixture of endocrine disruptors on attentional and executive functions in children.

Journal of the Endocrine Society·2026
Same author

Ethylene glycol determination in serum: comparison between enzymatic assay and GC-MS on real samples.

Clinical toxicology (Philadelphia, Pa.)·2026

Metal hip prostheses can release cobalt, potentially causing toxicity. This study found an average blood cobalt level of 2.51 µg/l in 251 patients, with 51 exceeding the 7 µg/l safety threshold.

Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Toxicology

Background:

  • Hip replacement surgery is common, with metal implants potentially releasing cobalt particles.
  • Cobalt release can lead to local (metallosis, hypersensitivity) and systemic (cardiomyopathy, neurological disorders) toxicity.
  • Annual monitoring, including blood cobalt levels, is recommended for patients with metal hip prostheses.

Purpose of the Study:

  • To assess blood cobalt concentrations in patients with metal hip prostheses.
  • To determine the prevalence of cobalt levels exceeding the recommended safety threshold.
  • To evaluate the performance of metal hip implants through cobalt monitoring.

Main Methods:

  • A 4-year study involving 251 patients who received metal hip prostheses.

More Related Videos

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report
07:45

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

3.9K
Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
09:31

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Published on: February 27, 2018

12.6K

Related Experiment Videos

Last Updated: Mar 15, 2026

Potentiodynamic Corrosion Testing
08:43

Potentiodynamic Corrosion Testing

Published on: September 4, 2016

18.5K
The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report
07:45

The Use of Mixed Reality in Custom-Made Revision Hip Arthroplasty: A First Case Report

Published on: August 4, 2022

3.9K
Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
09:31

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Published on: February 27, 2018

12.6K
  • Regular clinical and radiological examinations.
  • Determination of blood cobalt concentration (cobaltemia).

    • Main Results:

    • The average blood cobalt concentration was 2.51 µg/l.
    • 51 out of 251 patients (approximately 20.3%) had cobaltemia above the 7 µg/l threshold.
    • This indicates a significant proportion of patients may be at risk of cobalt toxicity.

    Conclusions:

    • While average cobalt levels were below the threshold, a notable percentage of patients exceeded it.
    • Regular monitoring of blood cobalt is crucial for early detection of potential implant-related toxicity.
    • Further research may be needed to refine implant design and monitoring protocols.