Related Experiment Video

Updated: Mar 15, 2026

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.6K

Migraine and type 2 diabetes; is there any association?

Fatemeh Sadat Haghighi1, Masoud Rahmanian2, Nasim Namiranian1

  • 1Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Journal of Diabetes and Metabolic Disorders
|September 13, 2016
PubMed
Abstract

Insights

Migraine prevalence is similar in type 2 diabetes mellitus (T2DM) patients and non-diabetics. However, T2DM duration and hypoglycemia attacks are linked to migraine in diabetic individuals.

Area of Science:

  • Neurology
  • Endocrinology
  • Epidemiology

Background:

  • Previous studies on migraine triggers in type 2 diabetes mellitus (T2DM) yielded contradictory results.
  • This study aimed to investigate migraine prevalence in T2DM patients compared to non-diabetics and identify predisposing factors.

Purpose of the Study:

  • To compare migraine prevalence between T2DM patients and a non-diabetic control group.
  • To identify factors associated with migraine in T2DM patients.

Main Methods:

  • 147 T2DM patients and 150 healthy individuals were enrolled in 2014.
  • Data collected via self-administered checklist including demographics, clinical characteristics, and ICHD-II migraine criteria.
  • Prevalence compared between groups, and associations with characteristics evaluated.

Main Results:

  • Migraine prevalence was 27.9% in T2DM patients and 26% in non-diabetics (p=0.406).
  • In T2DM patients, migraine correlated with family history, diabetes duration (especially 6-10 years), and hypoglycemia.
  • HbA1C, anti-diabetic medication, BMI, and age showed no significant association with migraine.

Conclusions:

  • No significant difference in migraine prevalence between T2DM and non-diabetic groups after age/sex adjustment.
  • Hypoglycemia attacks and T2DM duration are significant risk factors for migraine in T2DM patients.
  • Reducing hypoglycemia in long-standing T2DM may decrease migraine incidence.
Keywords:
MigrainePrevalenceType 2 diabetes mellitus

More Related Videos

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.2K
Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy08:47

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy

Published on: December 7, 2017

10.3K

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.3K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.1K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
14.8K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
5.8K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.6K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
596