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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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Augmentation cystoplasty in neurogenic bladder.

Bülent Çetinel1, Ervin Kocjancic2, Çetin Demirdağ1

  • 1Department of Urology, Istanbul University, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.

Investigative and Clinical Urology
|September 13, 2016
PubMed
Summary
This summary is machine-generated.

This review updates augmentation cystoplasty (AC) for neurogenic bladder, covering techniques, outcomes, and tissue engineering. Conventional AC remains vital for refractory neurogenic lower urinary tract dysfunction.

Keywords:
AugmentationBladderNeurogenic urinary bladder

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Area of Science:

  • Urology
  • Regenerative Medicine
  • Surgical Innovation

Background:

  • Neurogenic bladder significantly impacts lower urinary tract function.
  • Augmentation cystoplasty (AC) is a key surgical option for managing refractory cases.
  • Advances in tissue engineering offer potential new avenues for bladder reconstruction.

Purpose of the Study:

  • To provide an updated review of augmentation cystoplasty (AC) in neurogenic bladder.
  • To examine indications, contraindications, surgical techniques, and complications.
  • To explore the role and progress of tissue engineering in AC.

Main Methods:

  • Comprehensive literature search of PubMed/MEDLINE using keywords: "augmentation cystoplasty," "neurogenic bladder," and "bladder augmentation."
  • Review of identified articles and their reference lists for relevant literature.
  • Synthesis of current evidence on conventional and tissue-engineered AC.

Main Results:

  • Conventional AC remains a crucial surgical treatment for refractory neurogenic lower urinary tract dysfunction.
  • Significant progress has been made in tissue engineering approaches for AC.
  • The review details updated indications, contraindications, techniques, outcomes, and complications.

Conclusions:

  • Augmentation cystoplasty is essential for managing complex neurogenic bladder.
  • While tissue engineering shows promise, conventional AC maintains its importance.
  • Continued research is needed to optimize AC outcomes and explore regenerative solutions.