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Related Experiment Video

Updated: Mar 15, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Primary cutaneous angioplasmocellular hyperplasia.

Tapan K Dhali, Urmi Khanna1, Paschal D'Souza

  • 1ESIPGIMSR, Basaidarapur, New Delhi.

Dermatology Online Journal
|September 13, 2016
PubMed
Summary

Angioplasmocellular hyperplasia is a rare skin condition involving blood vessel growth and plasma cells. Clinicians must correlate clinical and pathological findings for accurate diagnosis due to its rarity.

Area of Science:

  • Dermatopathology
  • Vascular Biology

Background:

  • Angioplasmocellular hyperplasia is a rare condition characterized by vascular proliferation and plasma cell infiltration.
  • Fewer than 20 cases of cutaneous angioplasmocellular hyperplasia have been documented in English literature, highlighting its rarity.

Observation:

  • A 65-year-old male presented with a long-standing, asymptomatic, flesh-colored, ulcerated nodule on his back.
  • Histopathological examination of the lesion was performed.

Findings:

  • The histopathology revealed a dermal vascular proliferation.
  • A polyclonal plasma cell infiltrate was observed alongside the vascular proliferation.
  • The findings supported a diagnosis of angioplasmocellular hyperplasia.

Implications:

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  • This case underscores the rarity of cutaneous angioplasmocellular hyperplasia.
  • Accurate diagnosis requires careful clinico-pathological correlation to distinguish it from other cutaneous plasma cell conditions.
  • Further research may be needed to understand the pathogenesis and optimal management of this rare entity.