Segmental lesions along blaschko´s lines in an elderly man

Area of Science:

• Dermatology
• Genetics
• Genodermatoses

Background:

• Darier disease (DD) is an autosomal dominant genodermatosis.
• Characterized by keratotic papules on seborrheic areas, with potential oral, palmoplantar, and nail involvement.
• Segmental subtypes (type 1 and 2) are rare, typically presenting in middle age with lesions along Blaschko's lines.

Observation:

• This report describes an elderly male patient.
• The patient presented with extensive, multi-segmental Darier disease type 1.
• This presentation is clinically atypical for DD, particularly regarding age of onset.

Findings:

• The case demonstrates an unusual clinical manifestation of Darier disease type 1.
• Extensive segmental involvement in an elderly individual is a rare occurrence.
• This case expands the known spectrum of DD presentations.

Implications:

• Dermatologists should consider extensive segmental Darier disease type 1 in elderly patients.
• Recognizing atypical presentations is crucial for timely diagnosis and management.
• This case contributes to understanding the variability of genodermatoses.