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Related Concept Videos

Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

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In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
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Alcohols are organic compounds in which a hydroxy group is attached to a saturated carbon. Phenols are a class of alcohols containing a hydroxy group attached to an aromatic ring. The physical properties of the alcohols and phenols are influenced by hydrogen bonding due to the oxygen–hydrogen dipole in the hydroxy functional group and dispersion forces between alkyl or aryl regions of alcohol and phenol molecules.
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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Polyphenols and Sunburn.

Suzana Saric1, Raja K Sivamani2

  • 1School of Medicine, University of California, Davis, Sacramento, CA 95817, USA. ssaric@ucdavis.edu.

International Journal of Molecular Sciences
|September 13, 2016
PubMed
Summary
This summary is machine-generated.

Polyphenols, found in foods like green tea, may protect skin from sunburns. Both topical and oral forms show potential benefits against UV damage, though more research is needed.

Keywords:
UVAUVBantioxidantflavonoidspolyphenolsskin damagesunburns

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Area of Science:

  • Dermatology
  • Nutraceuticals
  • Photoprotection

Background:

  • Polyphenols are antioxidant compounds present in various foods and beverages.
  • They possess antioxidant, anti-inflammatory, and antineoplastic properties.
  • Emerging research suggests polyphenols may mitigate skin damage from ultraviolet (UVA and UVB) radiation.

Purpose of the Study:

  • To review existing evidence on the efficacy of topical and orally ingested polyphenols for sunburn prevention.
  • To synthesize findings from studies investigating polyphenol-based photoprotection.

Main Methods:

  • A systematic literature search was conducted on the PubMed database for studies on polyphenols and sunburn.
  • Fifteen studies out of 27 identified met the inclusion criteria.
  • Studies included human and animal models, evaluating topical, oral, or combined polyphenol administration.

Main Results:

  • Polyphenol sources included green tea, cocoa, grape seeds, and others.
  • Green tea was the most frequently studied polyphenol source.
  • Evidence suggests both topical and oral polyphenols may offer protection against UV-induced skin damage and sunburn.

Conclusions:

  • Polyphenols demonstrate potential as a protective agent against UV radiation and sunburn.
  • Further research is essential to determine optimal forms, concentrations, efficacy, and safety profiles.
  • Polyphenols may contribute to overall skin health by reducing UV damage.