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[Malignant bone marrow infiltration in nuclear magnetic resonance tomography]
A Gamillscheg1, C Urban, G Ranner
1Universitäts-Kinderklinik, Graz.
Summary
Magnetic resonance imaging (MRI) detects bone marrow changes by assessing signal intensity. This non-invasive technique identified cellular infiltration in two patients, leading to diagnoses of leukemia and neuroblastoma.
Area of Science:
- Radiology
- Oncology
- Pediatric Imaging
Background:
- Magnetic resonance imaging (MRI) is the sole non-invasive modality for evaluating bone marrow composition.
- Yellow bone marrow exhibits high signal intensity, mimicking subcutaneous fat.
- Cellular infiltration of bone marrow replaces fat cells, resulting in decreased signal intensity on MRI.