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Ruptured Gastric Aneurysm in α-1 Antitrypsin Deficiency
Veeravich Jaruvongvanich1, Ittikorn Spanuchart1, T Scott Gallacher1
1Internal Medicine, University of Hawaii, Honolulu, HI.
Abstract:
We present a unique vascular complication of α-1 antitrypsin deficiency (AATD) in a patient with an acute onset of epigastric pain and hemodynamic instability. Abdominal computed tomography angiography detected hemoperitoneum and hematoma within the gastrohepatic ligament with active extravasation. Abdominal angiography revealed left gastric aneurysms. An association between AATD and vascular aneurysms has been suggested to be secondary to unopposed proteolytic activity against arterial structural proteins. The aneurysm formation in aortic, superior mesenteric, inferior mesenteric, and splenic arteries has been reported. We report the first case with ruptured gastric artery aneurysm as a complication of AATD.
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