Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Translesion DNA Polymerases02:10

Translesion DNA Polymerases

11.5K
Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...
11.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interpreting non-semielliptical complex bands.

Journal of physics. Condensed matter : an Institute of Physics journal·2022
Same author

Complex band structure and electronic transmission eigenchannels.

The Journal of chemical physics·2017
Same author

A unified perspective of complex band structure: interpretations, formulations, and applications.

Journal of physics. Condensed matter : an Institute of Physics journal·2016
Same author

Quantitative Interpretations of Break Junction Conductance Histograms in Molecular Electron Transport.

ACS nano·2015
Same author

Communication: Finding destructive interference features in molecular transport junctions.

The Journal of chemical physics·2014
Same author

Response to "Comment on 'Rethinking first-principles electron transport theories with projection operators: the problems caused by partitioning the basis set'" [J. Chem. Phys. 140, 177103 (2014)].

The Journal of chemical physics·2014

Related Experiment Video

Updated: Mar 15, 2026

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

8.7K

Estimating the Landauer-Büttiker transmission function from single molecule break junction experiments.

Stephen E Tschudi1, Matthew G Reuter

  • 1Department of Applied Mathematics & Statistics and Institute for Advanced Computational Science, Stony Brook University, Stony Brook, NY 11794, USA.

Nanotechnology
|September 14, 2016
PubMed
Summary

This study develops statistical tools to compare molecular electronic transport experiments and computations. It enables quantitative estimation of the Landauer-Büttiker transmission function from experimental data, bridging a critical gap in molecular electronics research.

More Related Videos

Single-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage
09:53

Single-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage

Published on: February 7, 2021

2.5K
Author Spotlight: Developing Novel Anticancer Therapeutics Targeting the DNA Damage Response
05:01

Author Spotlight: Developing Novel Anticancer Therapeutics Targeting the DNA Damage Response

Published on: June 14, 2024

2.4K

Related Experiment Videos

Last Updated: Mar 15, 2026

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

8.7K
Single-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage
09:53

Single-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage

Published on: February 7, 2021

2.5K
Author Spotlight: Developing Novel Anticancer Therapeutics Targeting the DNA Damage Response
05:01

Author Spotlight: Developing Novel Anticancer Therapeutics Targeting the DNA Damage Response

Published on: June 14, 2024

2.4K

Area of Science:

  • Molecular electronics
  • Quantum transport
  • Statistical physics

Background:

  • Experiments measure molecular conductance, while computations predict transmission probability.
  • Comparing experimental and computational results is challenging due to data type differences (statistical vs. deterministic).
  • Existing methods lack rigorous statistical comparison for molecular electron transport.

Purpose of the Study:

  • To develop tools for quantitatively estimating Landauer-Büttiker transmission functions from experimental statistics.
  • To enable rigorous statistical comparisons between experimental and computational data in molecular electron transport.
  • To bridge the gap between experimental measurements and theoretical predictions in molecular electronics.

Main Methods:

  • Developed novel statistical tools to estimate transmission function shape with error bars.
  • Utilized experimental statistics from conductance and thermopower measurements.
  • Applied developed tools to existing molecular electron transport datasets.

Main Results:

  • Successfully estimated Landauer-Büttiker transmission functions directly from experimental statistics.
  • Demonstrated quantitative, statistically rigorous comparisons between experiment and computation.
  • Provided a method to overcome the deterministic vs. statistical data discrepancy.

Conclusions:

  • The developed tools facilitate accurate comparison of experimental and computational results in molecular electron transport.
  • This work advances the understanding and reliability of molecular electronic device characterization.
  • Enables more precise validation of theoretical models against experimental observations.