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Updated: Mar 15, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
Published on: January 19, 2020
Correctly identifying responses is critical for understanding homeostatic and allostatic regulation
Douglas S Ramsay1, Karl J Kaiyala2, Stephen C Woods3
1Department of Oral Health Sciences; University of Washington; Seattle, WA USA; Department of Orthodontics; University of Washington; Seattle, WA USA; Department of Pediatric Dentistry; University of Washington; Seattle, WA USA.
Abstract:
Homeostasis stabilizes critical biological variables within appropriate limits via corrective regulatory effector responses that adequately counter disturbing effects. Identifying individual effects and responses, and distinguishing their individual influences on a regulated state, is challenging. Studying effector responses can reveal regulatory phenomena that depart from homeostasis into the realm of allostasis.
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