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Sigmoid-vaginal fistula during bevacizumab treatment diagnosed by fistulography
C Hayashi1, S Takada2, A Kasuga2
1Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan. hayashi.chuyu@nihon-u.ac.jp.
What Is Known And Objective:
There have been several reports describing rectovaginal fistula development after bevacizumab treatment, and these fistulas were diagnosed by CT scan or colonoscopy. We report a case of sigmoid-vaginal fistula diagnosed by fistulography.
Case Description:
The case is a 53-year-old woman who was treated for chronic myelogenous leukaemia and gynaecological cancers 8 years previously. At 52 years of age, she was diagnosed with colon cancer and had a partial colectomy performed. One year after surgery, colon cancer recurred, and she was treated with anticancer agents, including bevacizumab. During chemotherapy, she complained of a foul smelling discharge from the vagina. Fistulography revealed a sigmoid-vaginal fistula.
What Is New And Conclusion:
This is the first report of vaginal fistulography performed on a patient who was treated with bevacizumab. Fistulography may be useful for detecting sigmoid-vaginal fistula.
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