Related Experiment Video
Updated: Mar 15, 2026
10:33
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
3.3K
Bilateral panuveitis associated with Whipple disease - case report.
Maria Lisboa1, Isabel Domingues1, Jaime Pamplona2
1Ophthalmology Department, Centro Hospitalar de Lisboa Central EPE, Lisbon, Portugal.
GMS Ophthalmology Cases
|September 15, 2016
Summary
Whipple disease, a rare condition, can present with neurological and ocular symptoms like panuveitis and stroke. Early diagnosis and treatment are crucial for improving patient outcomes.
Area of Science:
- Ophthalmology
- Neurology
- Infectious Diseases
Background:
- Whipple disease is a rare, systemic infectious disease caused by Tropheryma whipplei.
- It commonly affects the gastrointestinal tract but can manifest with diverse neurological and ocular symptoms.
Observation:
- A 65-year-old male presented with decreased visual acuity, hearing loss, vertigo, and limb weakness.
- Clinical examination revealed bilateral panuveitis and an ischemic cerebellar stroke.
Findings:
- Diagnosis was confirmed via histopathological analysis of adenopathy.
- The patient showed significant clinical improvement following cortico-antibiotic therapy.
Implications:
- Whipple disease should be considered in cases of unexplained panuveitis, even without typical gastrointestinal symptoms.
- Prompt diagnosis and treatment are vital to prevent potentially fatal complications.
Related Concept Videos
01:29Chronic Pancreatitis II: Collaborative Care
456
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
456
01:24Chronic Pancreatitis I: Introduction
842
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
842
01:30Inflammatory Bowel Disease II: Crohn's Disease
1.4K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.4K
01:25Endocarditis II: Clinical Features of Infective Endocarditis
687
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
687
01:27Acute Pancreatitis I: Introduction
1.4K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.4K
01:26Nephrotic Syndrome II : Assessment and Medical Management
294
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
294