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    The least absolute shrinkage operator (lasso) and gradient boosting offer similar performance for variable selection and prediction accuracy in high-dimensional data. Lasso is faster, while boosting is more modular for extensions.

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    Area of Science:

    • Biomedical research
    • Statistical modeling
    • High-dimensional data analysis

    Background:

    • Penalization and regularization techniques are crucial for statistical modeling with high-dimensional data.
    • Algorithms with automatic variable selection, such as the least absolute shrinkage operator (lasso) and statistical boosting, are gaining prominence.

    Purpose of the Study:

    • This study compares lasso and gradient boosting, two common techniques for variable selection in linear regression.
    • The comparison is conducted from both methodological and practical viewpoints.

    Main Methods:

    • The study describes lasso and gradient boosting, identifying conditions where their results converge in low-dimensional settings.
    • Extensive simulations evaluate performance in scenarios with more predictors than observations, varying noise-to-signal ratios and coefficient numbers.
    • The impact of different tuning methods on the outcomes is also examined.

    Main Results:

    • Both lasso and boosting perform penalization and variable selection for high-dimensional data, often yielding highly similar models.
    • Lasso offers a faster computation time.
    • Gradient boosting's modular design facilitates extensions to other regression models.

    Conclusions:

    • Despite differing optimization and regularization strategies, lasso and gradient boosting impose comparable constraints on estimation.
    • Both methods demonstrate similar practical performance in prediction accuracy and variable selection for high-dimensional datasets.