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Updated: Mar 15, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

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The Relationship of Carotid Arterial Stiffness and Left Ventricular Concentric Hypertrophy in Hypertension

Joanna Jaroch1, Krystyna Łoboz-Grudzień1,2, Stefania Magda3

  • 1Department of Cardiology, T. Marciniak Lower Silesian Hospital, Wrocław, Poland.

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University
|September 15, 2016
PubMed

Insights

Concentric hypertrophy (CH) in hypertension is linked to arterial stiffness and wave reflection, independent of blood pressure and diabetes. This finding highlights vascular damage as a key factor in CH prognosis.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Hypertension Research

Background:

  • Left ventricular hypertrophy (LVH) presents diverse geometric patterns influenced by hemodynamic profiles.
  • Concentric hypertrophy (CH), a specific LVH pattern, is associated with a poorer prognosis.

Purpose of the Study:

  • To investigate the association between carotid artery stiffness and CH in hypertensive patients.
  • To determine if carotid artery stiffness is an independent predictor of CH, beyond demographic, clinical, and hemodynamic factors.

Main Methods:

  • 262 subjects (202 hypertensive, 60 controls) underwent echocardiography and carotid ultrasound.
  • Hypertensive patients were classified into four LVH geometry patterns: normal, concentric remodeling, CH, and eccentric hypertrophy.
  • Carotid artery stiffness parameters (e.g., AI, PWVβ) and intima-media thickness (IMT) were assessed.

Main Results:

  • Multivariate analysis identified the augmentation index (AI) and pulse wave velocity (PWVβ) as independent predictors of CH.
  • Systolic blood pressure and diabetes were also independently associated with CH occurrence.
  • Carotid arterial stiffness and wave reflection parameters showed a strong association with CH.

Conclusions:

  • Concentric hypertrophy in hypertension is significantly associated with carotid arterial stiffness and wave reflection.
  • These vascular parameters are independent predictors of CH, even when accounting for blood pressure and diabetes.
  • Carotid artery stiffness serves as a valuable marker for vascular damage in hypertensive individuals with CH.
Abstract

Keywords:
arterial stiffnesshypertensionleft ventricular concentric hypertrophy

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