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Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate

I-Chung Chen1, Christine Hernandez1, Xueping Xu2

  • 11 Department of Biology, University of Texas at San Antonio , San Antonio, Texas.

Stem Cells and Development
|September 15, 2016
PubMed
Summary

Pluripotent stem cells maintain better genetic integrity than differentiated cells. This genetic stability dynamically changes with cell state transitions, crucial for clinical applications.

Keywords:
DNA repaircell fate transitionsmutationsstem cells

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