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Updated: Mar 15, 2026

Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test
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Much more than just another guidance document.

K Kulkarni1

  • 1Department of Pediatrics, Division of Hematology/Oncology, IWK Health Centre, Halifax, Nova Scotia, Canada.

Journal of Thrombosis and Haemostasis : JTH
|September 15, 2016
PubMed
Summary
This summary is machine-generated.

Developing pediatric thrombosis guidelines for central venous catheters involved significant learning and challenges. This experience highlighted opportunities for improving research acumen and clinical practice in high-risk pediatric populations.

Keywords:
central venous catheterearly career task forceguidelinesliterature reviewmentorship

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Area of Science:

  • Pediatric Hematology Oncology
  • Thrombosis Research
  • Clinical Guideline Development

Background:

  • Guideline development for pediatric central venous catheter thromboprophylaxis was undertaken by an early career researcher.
  • Focus on high-risk pediatric populations with thrombosis interests.

Discussion:

  • The process involved a steep learning curve in research acumen.
  • Personal experiences, lessons learned, and challenges encountered were significant.
  • The author's involvement extended beyond standard guideline writing.

Key Insights:

  • Successful development of a guidance document on pediatric thromboprophylaxis.
  • Gained valuable experience in research methodology and clinical guideline creation.
  • Identified key opportunities and challenges in pediatric thrombosis research.

Outlook:

  • Potential for improved thromboprophylaxis strategies in pediatric patients.
  • Future research directions in pediatric thrombosis and catheter-related complications.
  • Enhancing clinical practice through evidence-based guidelines.