[Effects of splenectomy on changes in hemorrheologic parameters following coronary occlusion in dogs]

Effects of splenectomy on changes of hemorrheologic parameters in the early stage of myocardial ischemia were observed in dogs. The results showed that splenectomy alleviated the increase in hematocrit and high shear viscosity of whole blood (r = 230 s-1) during 120 min of myocardial ischemia induced by coronary occlusion. Splenectomy reduced the increase in low shear viscosity of whole blood (r = 5.75 s-1) at 40 min and 80 min post-occlusion, but did not affect it at 120 min post-occlusion. Splenectomy had no effect on changes in blood viscosity fibrinogen concentration and plasma viscosity following coronary occlusion.