Novel embryo selection techniques to increase embryo implantation in IVF attempts

Area of Science:

• Reproductive Medicine
• Embryology
• In Vitro Fertilization (IVF)

Background:

• IVF success hinges on multiple stages, with embryo selection being a critical laboratory responsibility.
• Historically, embryo selection relied on morphology, but newer data is being integrated.

Purpose of the Study:

• To review current embryo selection methods used in IVF.
• To present the predictive capabilities of various embryo selection techniques.

Main Methods:

• A comprehensive literature search was conducted across major databases (PubMed, Medline, Cochrane).
• No time restrictions were applied to the search parameters.

Main Results:

• Combining morphological assessment with embryo kinetics from time-lapse technology offers reliable embryo quality insights.
• Blastocyst biopsy followed by comprehensive chromosome analysis identifies euploid embryos with higher implantation potential.

Conclusions:

• Embryo time-lapse imaging and blastocyst biopsy with comprehensive chromosome analysis show promise for increasing IVF pregnancy rates.
• These technologies may also reduce the incidence of multiple pregnancies, though further research is needed for routine implementation.