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Published on: May 23, 2025
Helicobacter pylori status among patients undergoing gastroscopy in rural northern Alberta
Isabelle N Colmers-Gray1, Ben Vandermeer2, Robert I Greidanus3
1Medical student at the University of Alberta in Edmonton at the time of the study, and is now an emergency medicine resident.
Objective:
To determine the Helicobacter pylori status of patients who underwent gastroscopy.
Design:
Retrospective chart review.
Setting:
Peace River Community Health Centre in rural northwestern Alberta.
Participants:
Data were collected from patients who had a gastroscopy performed by either of 2 family physicians between January 1, 2011, and December 31, 2012.
Main Outcome Measures:
The proportion of patients who had positive test results for H pylori overall and among first-time gastroscopy patients. For first-time gastroscopy patients, the associations between H pylori infection and patient age, sex, residence, and procedural indications and findings were explored.
Results:
A total of 251 gastroscopies were conducted in 229 unique patients during the study period. Overall, 12.4% (95% CI 8.3% to 16.4%) of patients had positive results for H pylori and among the 159 first-time gastroscopy patients, 17.6% (95% CI 11.7% to 23.5%) had positive test results for H pylori. Helicobacter pylori status did not differ significantly by geography, sex, or age. The prevalence of H pylori was higher among patients with H pylori-related indications for gastroscopy (such as dyspepsia and upper gastrointestinal tract bleeding) than among patients with other indications; however, H pylori infection was not statistically significantly greater in patients diagnosed with peptic ulcer disease.
Conclusion:
The prevalence of H pylori infection among patients undergoing gastroscopy in rural northern Alberta appears lower than other Canadian estimates. In regions with low H pylori rates, patients with dyspepsia might be better served by acid suppression and nonsteroidal anti-inflammatory drug cessation before investigating for H pylori infection. Population-based research is required to further describe regional differences in H pylori rates.
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