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[Reference intervals of hematologic parameters in the elderly].

B Chomón, L Vázquez, D Castro

    Sangre
    |June 1, 1989
    PubMed
    Summary
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    This study analyzed blood parameters in older adults, finding significant sex-based differences in most values. Hemoglobin in men and platelet count in women showed age-related declines.

    Area of Science:

    • Gerontology
    • Hematology
    • Clinical Biochemistry

    Context:

    • Aging population necessitates understanding age-related physiological changes.
    • Establishing reference ranges for blood parameters in older adults is crucial for accurate diagnosis.
    • Sex-based variations in hematological parameters require specific consideration in elderly populations.

    Purpose:

    • To determine reference intervals for key hematological and serum iron parameters in individuals aged 60-89 years.
    • To investigate sex-specific differences in these blood parameters within the elderly cohort.
    • To explore age-related trends and correlations for selected hematological values.

    Summary:

    • Evaluated red blood cell counts, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelet counts, plateletcrit, PDW, WBC counts, differential WBC counts, and serum iron in 167 adults (60-89 years).

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  • Identified significant sex differences for most parameters, excluding RDW, platelet count, and WBC differential percentage.
  • Observed age-related decreases in hemoglobin for men, and inverse correlations for hemoglobin, RBC count, and hematocrit in men, and platelet count in women.

    • Impact:

    • Provides essential reference intervals for hematological parameters in older adults, aiding clinical interpretation.
    • Highlights the importance of considering sex and age when evaluating blood test results in the elderly.
    • Contributes to a better understanding of age-associated hematological changes and their clinical relevance.