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Is peripheral access for apheresis procedures underutilized in clinical practice?-A single centre experience
Daniel Putensen1, David Leverett1, Bhavika Patel1
1University College London Hospitals, Haematology-Apheresis, London, United Kingdom.
Peripheral venous access is effective for most elective apheresis procedures, including hematopoietic progenitor cell harvests and automated red cell exchange. This approach offers a viable alternative to central venous access in many clinical scenarios.
Area of Science:
- Vascular Access
- Apheresis Procedures
- Hematology
Background:
- Literature suggests peripheral venous access is primary for apheresis, but clinical practice varies.
- Central venous access is mandated for critically ill patients or by patient preference.
- Peripheral access is proposed as feasible for most elective apheresis procedures.
Purpose of the Study:
- To assess the feasibility and suitability of peripheral vascular access.
- To evaluate peripheral access for diverse apheresis procedures.
- To analyze access methods in both elective and emergency settings.
Main Methods:
- Retrospective analysis of vascular access device and cannulation site selection.
- Data collected from all apheresis procedures over a two-year period (January 2014 - December 2015).
- Single-institution study.
Main Results:
- 72% of 3714 total apheresis procedures utilized peripheral access.
- Peripheral access rates varied by procedure: 88-97% for hematopoietic progenitor cell harvests, 93% for mononuclear cell harvest, 80% for automated red cell exchange, 26% for therapeutic plasma exchange, and 71% for white blood cell depletion.
- Elective procedures showed higher peripheral access rates, ranging from 80% to 97%.
Conclusions:
- The majority of elective apheresis procedures can be successfully performed using peripheral vascular access.
- Peripheral access is a practical and effective option for numerous apheresis types.
- Findings support increased utilization of peripheral access for elective apheresis.
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