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Retrospective Multicenter Study on Risk Factors for Surgical Site Infections after Appendectomy for Acute
Louis J X Giesen1, Anne Loes van den Boom, Charles C van Rossem
1Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands.
Background:
Surgical site infections (SSI) are seen in up to 5% of patients after appendectomy for acute appendicitis. SSI are associated with prolonged hospital stay and increased costs. The aim of this multicenter study was to identify factors associated with SSI after appendectomy for acute appendicitis.
Methods:
Patients who underwent appendectomy for acute appendicitis between June 2014 and January 2015 in 6 teaching hospitals in the southwest of the Netherlands were included. Patient, diagnostic, intra-operative and disease-related factors were collected from the patients' charts. Primary outcome was surgical site infection. Multivariable logistic regression was performed to identify independent risk factors for SSI.
Results:
Some 637 patients were included. Forty-two patients developed a SSI. In univariable analysis body temperature >38°C, CRP>65 and complex appendicitis were associated with SSI. After multivariable logistic regression with stepwise backwards elimination, complex appendicitis was significantly associated with SSI (OR 4.09; 95% CI 2.04-8.20). Appendiceal stump closure with a stapler device was inversely correlated with SSI (OR 0.40; 95% CI 0.24-0.97) Conclusions: Complex appendicitis is a risk factor for SSI and warrants close monitoring postoperatively. The use of a stapler device for appendiceal stump closure is associated with a reduced risk of SSI.
Insights
Complex appendicitis increases surgical site infection (SSI) risk after appendectomy. Using a stapler device for appendiceal stump closure may reduce SSI, aiding patient recovery and lowering healthcare costs.
Area of Science:
- General Surgery
- Infectious Disease Epidemiology
Background:
- Surgical site infections (SSI) affect up to 5% of patients post-appendectomy.
- SSI lead to extended hospital stays and increased healthcare expenditures.
Purpose of the Study:
- To identify independent risk factors for SSI following appendectomy for acute appendicitis.
- To evaluate the association of appendiceal stump closure methods with SSI rates.
Main Methods:
- Multicenter study including 637 patients undergoing appendectomy for acute appendicitis.
- Data collected included patient, diagnostic, intra-operative, and disease-related factors.
- Multivariable logistic regression analysis identified independent risk factors for SSI.
Main Results:
- Complex appendicitis was a significant independent risk factor for SSI (OR 4.09).
- Appendiceal stump closure using a stapler device showed an inverse correlation with SSI (OR 0.40).
Conclusions:
- Complex appendicitis is a significant risk factor for SSI, necessitating vigilant postoperative monitoring.
- Stapler device use for appendiceal stump closure is associated with a decreased risk of SSI.
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