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Published on: April 7, 2015
Neisseria meningitidis presenting as acute abdomen and recurrent reactive pericarditis
Karolina Akinosoglou1, Angelos Alexopoulos2, Nikolaos Koutsogiannis3
1Medical School of Patras, University Hospital, Department of Internal Medicine, Rio, Greece; Medical School of Patras, University Hospital, Department of Infectious Diseases, Rio, Greece.
Abstract:
Meningococcal meningitis is a well established potential fatal infection characterized by fever, headache, petechial rash, and vomiting in the majority of cases. However, protean manifestations including abdominal pain, sore throat, diarrhea and cough, even though rare, should not be overlooked. Similarly, although disseminated infection could potentially involve various organ-targets, secondary immune related complications including joints or pericardium should be dealt with caution, since they remain unresponsive to appropriate antibiotic regimens. We hereby report the rare case of an otherwise healthy adult female, presenting with acute abdominal pain masking Neisseria meningitidis serotype B meningitis, later complicated with recurrent reactive pericarditis despite appropriate antibiotic treatment. There follows a review of current literature.
Insights
Meningococcal meningitis can present with unusual symptoms like abdominal pain. This case highlights a rare Neisseria meningitidis serotype B infection complicated by reactive pericarditis, even after antibiotic treatment.
Area of Science:
- Infectious Diseases
- Microbiology
- Immunology
Background:
- Meningococcal meningitis is a serious infection, typically presenting with fever, headache, and rash.
- While classic symptoms are common, atypical presentations such as abdominal pain can occur.
- Disseminated meningococcal disease can affect multiple organs and lead to immune-related complications.
Observation:
- A rare case of Neisseria meningitidis serotype B meningitis presented initially as acute abdominal pain in a healthy adult female.
- The patient developed recurrent reactive pericarditis despite receiving appropriate antibiotic therapy.
- This case underscores the importance of considering meningitis in patients with unusual symptoms.
Findings:
- Neisseria meningitidis serotype B can manifest with protean symptoms, including abdominal pain, mimicking other conditions.
- Secondary immune-related complications like pericarditis may occur and can be refractory to antibiotics.
- Early recognition of atypical meningococcal meningitis is crucial for timely and effective management.
Implications:
- Clinicians should maintain a high index of suspicion for meningococcal meningitis in patients with unexplained abdominal pain or other non-classical symptoms.
- The potential for antibiotic-unresponsive immune complications necessitates careful monitoring and management strategies.
- This case contributes to the understanding of the diverse clinical spectrum of meningococcal disease and its management challenges.
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