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Updated: Mar 15, 2026

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

Gold nanocrystals with DNA-directed morphologies.

Xingyi Ma¹, June Huh¹, Wounjhang Park²

¹Department of Chemical &Biological Engineering, Korea University, Seoul 136713, Republic of Korea.

Nature Communications

|September 17, 2016

Summary

This summary is machine-generated.

Researchers developed a DNA-guided method for precisely controlling the 3D structure of gold nanocrystals. This breakthrough enables the creation of complex nanomaterials for advanced nanobiotechnology applications.

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Last Updated: Mar 15, 2026

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

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Published on: September 27, 2019

Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures

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Published on: June 26, 2020

Area of Science:

Nanotechnology
Materials Science
Biotechnology

Background:

Precise control over metal nanomaterial structure is crucial for advanced nanobiotechnology.
While nanoparticle assembly methods are established, synthesizing 3D nanocrystals with controlled structures remains a significant challenge.

Purpose of the Study:

To demonstrate a novel method for directed crystallization of gold using DNA molecular regulators.
To explore the application of this method in achieving three-dimensional topological control of crystalline nanostructures.

Main Methods:

Utilizing single DNA molecular regulators for sequence-independent, directed crystallization of gold.
Anchoring DNA onto gold nanoseeds with varied alignments to dictate nanocrystal topology.
Characterizing the resulting asymmetric and complex 3D nanostructures.

Main Results:

Successfully synthesized gold nanocrystals with defined, controllable 3D topologies.
Generated diverse asymmetric structures, including pushpin-, star-, and biconcave disk-like forms, alongside complex jellyfish- and flower-like shapes.
Demonstrated the DNA-directed approach enables solution-based synthesis of 3D nanocrystals with directional control.

Conclusions:

DNA molecular regulators offer a powerful tool for sequence-independent synthesis of 3D nanocrystals.
This method expands the toolkit for designing and synthesizing feature-rich nanomaterials.
The approach holds significant potential for future translational biotechnology applications.