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[Late metastasis of an extragonadal Leydig cell tumor]

G Kleinhans1, G Cohausz, K G Dorst

  • 1Urologische Klinik, Westfälische Wilhelms-Universität Münster.

Der Urologe. Ausg. A
|July 1, 1989
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...