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The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...
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Self-Healing Molecular Crystals.

Patrick Commins1, Hideyuki Hara2, Panče Naumov3

  • 1New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.

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|September 17, 2016
PubMed
Summary
This summary is machine-generated.

This study presents the first evidence of self-healing in molecular crystals, specifically dipyrazolethiuram disulfide. These solid-state compounds demonstrated a 6.7% healing of mechanical damage after compression.

Keywords:
computed tomographycrystal engineeringdisulfidesself-healingsmart materials

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Area of Science:

  • Solid-state chemistry
  • Materials science
  • Polymer science

Background:

  • Materials exposed to mechanical stress are susceptible to damage like cracking and wearing.
  • Self-healing polymers can autonomously repair macroscopic damage, mimicking biological systems.
  • Self-healing research has largely focused on soft materials, neglecting solid-state organic chemistry.

Purpose of the Study:

  • To investigate the potential for self-healing properties in ordered solid-state compounds.
  • To demonstrate self-healing in a molecular crystal for the first time.
  • To expand the understanding of self-healing beyond mesophasic materials.

Main Methods:

  • Utilized molecular crystals of dipyrazolethiuram disulfide.
  • Applied mild compression to induce mechanical damage.
  • Quantified the degree of self-healing achieved.

Main Results:

  • Observed and quantified the first evidence of self-healing in a molecular crystal.
  • Dipyrazolethiuram disulfide crystals exhibited a 6.7% degree of healing after compression.
  • Demonstrated that self-healing is achievable in ordered solid-state materials.

Conclusions:

  • Self-healing capabilities can be extended to the domain of solid-state organic chemistry.
  • Molecular crystals possess the potential for autonomous repair of mechanical damage.
  • This research opens new avenues for developing self-healing solid-state materials.