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A new HLA-B antigen, BHT: definition by serological and biochemical means
A Hajek-Rosenmayr1, L Jungl, M Kirnbauer
1Institute for Blood Group Serology, University of Vienna, Austria.
Vox Sanguinis
|January 1, 1989
Abstract:
In 3 unrelated individuals, a new, so far unknown HLA-B-locus antigen was found. This HLA-B antigen, provisionally termed 'BHT', is recognized by extra reactions with alloantisera against the B5 cross-reactive group. BHT can be clearly discerned from all cross-reactive antigens by one-dimensional isoelectro focusing (1D IEF), as it reveals, on IEF gels, a characteristic, rather neutral double-banding pattern different from all known HLA class I bands. The BHT banding pattern, which is identical in all 3 BHT-positive individuals, segregates with the haplotype A28, BHT, Cw7, DRw6.