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[The use of Pantogam syrup in treating small children's breath holding spells]

A V Polskaya1, L S Chutko1, E V Jakovenko1

  • 1Institute of Human Brain, Russian Academy of Sciences, St. Petersburg, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|September 17, 2016
PubMed

Insights

Pantogam syrup (hopantenic acid) effectively treats breath-holding spells (BHS) in children. This neuroprotective therapy significantly improved clinical symptoms and reduced anxiety compared to psychological methods alone.

Area of Science:

  • Pediatric Neurology
  • Pharmacology

Background:

  • Breath-holding spells (BHS) are common in young children.
  • Anxiety and neurophysiological abnormalities are associated with BHS.

Purpose of the Study:

  • To evaluate the efficacy of pantogam syrup 10% (hopantenic acid) for treating BHS in children.
  • To assess the impact of pantogam on clinical manifestations, anxiety, and neurophysiological indicators.

Main Methods:

  • A study involving 60 children aged 2-4 years with BHS.
  • Division into two groups: a main group receiving pantogam syrup and a control group receiving psychological methods.
  • Evaluation included clinical assessment, anxiety level measurement, and long-term video-EEG monitoring.

Main Results:

  • Clinical improvement observed in 73.3% of children treated with pantogam syrup, versus 16.7% in the control group.
  • Significant reduction in anxiety levels following neuroprotective therapy.
  • EEG analysis showed decreased slow rhythms and improved brain functional maturity in the pantogam group.

Conclusions:

  • Pantogam syrup demonstrates high efficacy in treating pediatric BHS.
  • Hopantenic acid offers a beneficial neuroprotective effect.
  • Pantogam syrup is a promising therapeutic option for managing BHS in children.
Abstract

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