Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Cancer Therapies

Cancer Therapies

Chronic Pancreatitis II: Collaborative Care

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Nursing Ethical Principles II

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Understanding Equity in Cancer Prehabilitation Services in Wales: A Medical Record Review.

Cancer reports (Hoboken, N.J.)·2026

Same author

Parenteral nutrition in advanced cancer: A qualitative study on decision-making and information needs of patients and carers.

PloS one·2026

Same author

Use and impact of assistive devices in activities of daily living among adults with advanced respiratory disease: a secondary data analysis.

Disability and rehabilitation. Assistive technology·2026

Same author

Utilisation patterns of systemic anticancer therapy (SACT) in patients with advanced non-small cell lung cancer (NSCLC) in England.

BMJ oncology·2026

Same author

Maintaining function and participation through tailored 24-hour movement behaviours for people living with multiple long-term conditions and frailty (The PERSONAL-AGILITY study): Protocol for a randomised controlled feasibility trial.

PloS one·2026

Same author

Endoscopic ultrasound-guided transoesophageal pericardiocentesis: a case report on a therapeutic solution for pericardial tamponade with malignant posterior pericardial effusion.

Cardio-oncology (London, England)·2026

Same journal

Cortical and brainstem mechanisms of pain: linking defensive responses, descending modulation, and affective-sensory integration.

Current opinion in supportive and palliative care·2026

Same journal

Comparison of the EORTC QLQ-EN24, FACT-En, and FEnSI-23 for assessing quality of life in endometrial cancer: a systematic review.

Current opinion in supportive and palliative care·2026

Same journal

Dysphagia, aspiration, and respiratory problems in people with chronic respiratory illness.

Current opinion in supportive and palliative care·2026

Same journal

Decision-making and treatment planning for older adults with pre-existing cognitive impairment and cancer.

Current opinion in supportive and palliative care·2026

Same journal

Clinical decision support system for breathlessness.

Current opinion in supportive and palliative care·2026

Same journal

The prevalence of persisting breathlessness despite treatment in chronic conditions.

Current opinion in supportive and palliative care·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 15, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

Practical multimodal care for cancer cachexia.

Matthew Maddocks¹, Jane Hopkinson, John Conibear

¹aKing's College London, Cicely Saunders Institute, London, UK bSchool of Healthcare Sciences, Cardiff University, Cardiff, UK cOncology Department, St. Bartholomew's Hospital, London, UK dTherapies Department, The Royal Marsden NHS Foundation Trust, London, UK eDepartment of Surgery, Royal Infirmary, Edinburgh, UK.

Current Opinion in Supportive and Palliative Care

|September 17, 2016

Summary

This summary is machine-generated.

Cancer cachexia management requires a multimodal approach. Practical strategies integrating nutrition, exercise, and education can be implemented by healthcare teams to improve patient quality of life.

Related Experiment Videos

Last Updated: Mar 15, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Published on: November 30, 2016

Area of Science:

Oncology
Clinical Nutrition
Gerontology

Background:

Cancer cachexia significantly impairs patient function, treatment tolerance, and quality of life.
A multimodal approach is recommended for cachexia management due to its complex pathophysiology, yet practical implementation remains challenging.

Observation:

Four lung cancer cases illustrate multimodal cachexia management across different treatment phases (surgery, chemoradiotherapy, palliative chemotherapy, no active treatment).
Proposed multimodal care integrates nutritional support, exercise, and anti-inflammatory agents within personalized, family-centered oncology care.

Findings:

Multimodal care is a shared responsibility among healthcare professionals, emphasizing patient and family engagement.
Effective multimodal cachexia management can be achieved with simple interventions and does not necessitate a specialized team.

Implications:

Healthcare professionals can collectively build confidence and expertise to implement multimodal cachexia care.
Pragmatic testing of multimodal approaches, including alongside novel pharmacological treatments, is feasible.