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Related Experiment Video

Updated: Mar 15, 2026

Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)
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Zirconia in biomedical applications.

Yen-Wei Chen1, Joelle Moussi1, Jeanie L Drury1

  • 1a Department of Restorative Dentistry , University of Washington School of Dentistry , Seattle , WA , USA.

Expert Review of Medical Devices
|September 17, 2016
PubMed
Summary

This review explores the use of zirconia in medicine and dentistry, focusing on its physical and biological properties. Zirconia is used in hip replacements and dental restorations due to its wear resistance and esthetic appeal. However, concerns about fracture risks and long-term performance remain. The authors suggest that more clinical data is needed to address these concerns. The future of zirconia in biomedical fields depends on resolving these uncertainties.

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Area of Science:

  • Biomedical materials science
  • Dental prosthetics research
  • Orthopedic implant development

Background:

Zirconia has gained attention in biomedical fields due to its favorable properties. Prior research has shown that zirconia offers benefits in wear resistance and aesthetics. However, long-term clinical data remains limited. This gap motivated the need for updated reviews on zirconia's applications. No prior work had resolved concerns about fracture risks in implants. The demand for esthetically pleasing dental restorations has grown. Zirconia's use in prosthetics has expanded rapidly. This paper's contribution is to synthesize recent findings in this area.

Purpose Of The Study:

The aim of this review is to evaluate zirconia's role in biomedical applications. The focus is on dental and orthopedic uses of zirconia. The motivation stems from the need to address unresolved clinical concerns. Zirconia's wear resistance and esthetic appeal are key factors. Limited long-term data remains a challenge in the field. The study addresses gaps in understanding fracture risks. It also considers the impact of crystalline degradation. This work seeks to guide future clinical decisions.

Keywords:
Biocompatibilityall-ceramic crownsdentalendosseous implantsimplant abutmentsmonolithic crowns: low-temperature aging degradationorthopedicosseointegrationZirconia implantsBiomedical ceramicsDental restoration materialsOrthopedic implant wear resistance

Frequently Asked Questions

Zirconia offers superior wear resistance and esthetic appeal in dental and orthopedic uses.

Zirconia is used for its esthetic properties and ability to resist wear in crowns and implants.

The risk of catastrophic fracture remains a concern despite its wear resistance.

The review suggests that quality long-term clinical data remains scarce for zirconia applications.

Crystalline degradation, crack propagation, and wear effects may contribute to zirconia implant failure.

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Main Methods:

The authors conducted a literature review using the MEDLINE database. Articles published from 2010 to 2016 were included. Both original and review articles were considered. The focus was on dental and orthopedic applications. No specific exclusion criteria were mentioned. The approach involved synthesizing findings from the literature. Expert commentary was included to assess recent data. The review highlights unresolved clinical concerns.

Main Results:

Zirconia shows superior wear resistance in hip replacements compared to alternatives. Dental applications include implants, abutments, and crowns. Esthetic appeal has driven zirconia's adoption in dentistry. However, risks of catastrophic fracture persist in orthopedic use. Crystalline degradation and crack propagation remain debated issues. Long-term clinical data is still lacking for many applications. The review emphasizes the need for further studies. These findings suggest zirconia's potential but highlight uncertainties.

Conclusions:

The authors propose that zirconia performs well in biomedical settings. They suggest that concerns about fracture and degradation remain unresolved. No prior work has fully addressed these issues. The future of zirconia depends on generating more clinical data. The review does not claim zirconia is essential for all applications. It highlights the need for further research on wear effects. The authors do not propose new directions beyond data collection. They emphasize the importance of resolving current uncertainties.

The authors propose that future use of zirconia depends on resolving concerns through clinical data.