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[15N] ammonium test for liver function diagnosis
Zeitschrift Fur Medizinische Laboratoriumsdiagnostik
|January 1, 1989
Abstract:
The functional state of the liver can be assessed by oral administration of 15N labelled ammonium chloride (tracer) and subsequent isotope analysis of [15N]urea and [15N]ammonia in urine. Clinical tests based on the ratio of the excess abundances of [15N]ammonia to [15N]urea excreted in urine 3 hours after oral administration of the tracer gave values for patients with liver diseases which differed significantly from these of healthy subjects.