Related Experiment Video
Updated: Mar 15, 2026

Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium
Published on: March 4, 2016
Induced-Wedge Technique to Improve Liquid Embolic Agent Penetration into Spinal Dural Arteriovenous Fistula
Dae Chul Suh1, Su Hee Cho1, Ji Eun Park1
1Department of Radiology, University of Ulsan, College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.
Objective:
To promote embolization of spinal dural arteriovenous fistula (SDAVF) with a small long tortuous feeder that may impede successful application of an embolic agent.
Methods:
An induced-wedge technique was developed in which blood flow was blocked by coiling at the proximal part of the microcatheter for secure injection of N-butyl cyanoacrylate. We used this technique in 11 patients with SDAVF (male/female ratio, 8:3): 7 thoracic, 2 lumbar, 1 sacral, and 1 cervical. Clinical outcome was evaluated by the Aminoff-Logue Disability Scale.
Results:
Penetration of embolic agent through the fistula into the vein was complete (n = 5), nearly complete (no penetration of embolic agent into the vein but no residual fistula on 3 adjacent selective angiograms; n = 4), or partial (embolization with a small residual filling of the draining vein; n = 2). All patients improved neurologically during follow-up (median, 18 months; range, 7-37 months) and achieved complete recovery. Of the 2 patients who obtained partial obliteration, one showed disappearance of the residual lesion on angiography 21 months later and the other achieved complete results after repeat embolization.
Conclusions:
The induced-wedge technique can improve SDAVF embolization by providing better penetration of the liquid embolic agent to the fistula and vein.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Venous Thrombosis III: Interprofessional Care

