[Effect of allotransplantation of the testis on several metabolism parameters in primary hypogonadism]

The allotransplantation of a testis with immunological control and immunosuppressive treatment may ensure a quite satisfactory hormone compensation and acceptable sexual rehabilitation of patients suffering from primary hypogonadism. These patients show characteristic biochemical changes: reduction of testosterone, iron and calcium blood concentration and carbonic anhydrase activity, but increase of FSH, LH and oxyproline concentration, whereas content of copper and zinc and activity of transferrine and ceruloplasmin are normal. In cases of successful testicular allotransplantation normalization of the above mentioned biochemical parameters occur together with an improvement of blood hormone balance (increased level of testosterone and decreased FSH and LH levels).