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Attitudes toward antipsychotic medications as a useful feature in exploring medication non-adherence in schizophrenia
Ludovic Samalin1, Ingrid de Chazeron2, Olivier Blanc2
1CHU Clermont-Ferrand, University of Auvergne, EA 7280, Clermont-Ferrand, France; Fondation FondaMental, Créteil, France.
Objective:
To investigate the interest in the attitudes toward antipsychotic medication in exploring medication non-adherence.
Methods:
Schizophrenic patients (N=120) completed the Beliefs about Medicines Questionnaire and measures of medication adherence, and clinical outcomes. Comparison between four attitudinal groups and logistic regressions were performed.
Results:
High level of adherence varied significantly between attitudinal groups (Accepting, 70%; Indifferent, 63%; Ambivalent, 50%; Sceptical, 14%; p<0.001). Poor insight and psychic side effects were the most significant predictors of negative beliefs.
Conclusion:
The attitudinal groups approach could facilitate the identification of patients with non-adherence and determine individual targets of interventions to improve negative beliefs.
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