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Related Experiment Video

Updated: Jan 20, 2026

Harvest of Vestibular End-Organs under Physiologic Conditions during Labyrinthectomy
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Harvest of Vestibular End-Organs under Physiologic Conditions during Labyrinthectomy

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Menière's disease.

J M Espinosa-Sanchez1, J A Lopez-Escamez2

  • 1Otology and Neurotology Group, Department of Genomic Medicine, Centre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucia, Granada, Spain; Department of Otolaryngology, Hospital San Agustin, Linares, Jaen, Spain.

Handbook of Clinical Neurology
|September 18, 2016
PubMed
Summary
This summary is machine-generated.

Menière's disease (MD) is an inner ear disorder with genetic links, causing vertigo, hearing loss, and tinnitus. Treatment focuses on symptom relief and preventing further hearing damage.

Keywords:
BetahistineEndolymphatic hydropsIntratympanic gentamicinIntratympanic steroidsSensorineural hearing lossVertigo

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Area of Science:

  • Otolaryngology
  • Neurology
  • Genetics

Background:

  • Menière's disease (MD) is a chronic inner ear condition.
  • It involves episodic vertigo, sensorineural hearing loss, tinnitus, and aural pressure.
  • Genetic factors and various triggers like allergens or infections may play a role.

Purpose of the Study:

  • To summarize the understanding of Menière's disease.
  • To outline diagnostic criteria and management strategies.

Main Methods:

  • Diagnosis relies on clinical criteria, including episodic vertigo and hearing loss.
  • Audiologic and vestibular assessments aid in monitoring disease progression.

Main Results:

  • MD is characterized by fluctuating aural symptoms and can include headache.
  • Bilateral involvement occurs in 25-40% of patients.
  • Treatment aims to manage acute episodes and prevent hearing loss.

Conclusions:

  • Menière's disease is a complex disorder with multifactorial causes.
  • Current treatments are symptomatic and preventive, including lifestyle changes, medication, and surgery.