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Diagonal Method to Measure Synergy Among Any Number of Drugs
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Assessment of non-linear combination effect terms for drug-drug interactions

Gilbert Koch1,2, Johannes Schropp3, William J Jusko4

  • 1Pediatric Pharmacology and Pharmacometrics, University of Basel, Children's Hospital (UKBB), Spitalstrasse 33, 4056, Basel, Switzerland. gilbert.koch@ukbb.ch.

Journal of Pharmacokinetics and Pharmacodynamics
|September 18, 2016
PubMed

Keywords:
Bliss IndependenceCombination therapyDrug–drug interactionLoewe AdditivityOptimal concentration

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