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Updated: Mar 15, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Thoracic manifestation of tuberculosis]
1Abteilung für Allgemeine Radiologie und Kinderradiologie, Universitätsklinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich. daniela.kienzl-palma@meduniwien.ac.at.
Radiological imaging, including chest X-rays and CT scans, is crucial for diagnosing and monitoring thoracic tuberculosis (TB). Recognizing typical active TB findings on CT aids timely diagnosis and treatment.
Area of Science:
- Radiology
- Infectious Diseases
- Pulmonology
Background:
- Tuberculosis (TB) is a granulomatous disease caused by Mycobacterium tuberculosis, primarily affecting the thorax.
- Increasing TB incidence in Central Europe necessitates familiarity with its radiological manifestations to differentiate active from inactive disease.
- Immune status significantly influences TB's clinical and radiographic presentation, challenging traditional classifications.
Purpose of the Study:
- To summarize and discuss the radiographic manifestations of thoracic TB.
- To highlight the importance of radiological assessment in diagnosing and managing TB.
- To emphasize differentiating active from inactive TB based on imaging findings.
Main Methods:
- Review of radiographic manifestations of thoracic TB.
- Discussion of the role of chest X-ray imaging and computed tomography (CT) in TB detection and follow-up.
- Integration of medical history and bacteriological tests with imaging.
Main Results:
- Chest X-rays are the primary diagnostic tool for suspected TB screening, diagnosis, and therapy monitoring.
- CT scans offer higher sensitivity than X-rays for subtle parenchymal changes and lymph node involvement.
- Typical active TB findings on CT include tree-in-bud opacities, lobular consolidations, centrilobular nodules, cavities, and ground-glass opacities.
Conclusions:
- Chest X-rays should be the initial imaging modality for suspected TB.
- CT is recommended when active TB is suspected for detailed evaluation.
- Specific CT findings are indicative of active TB, guiding clinical management.
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