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Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Suicide and chronic kidney disease: a case-control study.

Chao-Han Liu1, Ming-Kung Yeh2,3, Shu-Chuan Weng4

  • 1Biomedical Engineering Program, Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|September 18, 2016
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Summary

Chronic kidney disease (CKD) and hemodialysis (HD) are linked to increased suicide risk. Early-phase HD patients face the highest risk, emphasizing the need for comprehensive patient assessment.

Keywords:
CKDdialysishaemodialysissuicide

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Area of Science:

  • Nephrology
  • Psychiatry
  • Public Health

Background:

  • The relationship between chronic kidney disease (CKD) and suicide risk is not fully understood.
  • Dialysis modalities and duration may influence suicide risk in CKD patients.

Purpose of the Study:

  • To determine the association between CKD and suicide.
  • To investigate suicide risk in patients undergoing different dialysis modalities and durations.

Main Methods:

  • Utilized Taiwan National Health Insurance Research Database (2000-2012).
  • Analyzed 51,642 suicide decedents and 206,568 matched living controls.
  • Employed conditional logistic regression, controlling for sociodemographic factors, comorbidities, and psychiatric disorders.

Main Results:

  • CKD was significantly associated with a 1.25-fold increased suicide risk (aOR=1.25, 95% CI=1.17-1.34).
  • Hemodialysis (HD) patients showed a 3.35-fold higher suicide risk (aOR=3.35, 95% CI=3.02-3.72).
  • Patients initiating dialysis within 0-3 months had a markedly elevated risk (aOR=20.26, 95% CI=15.99-25.67).

Conclusions:

  • CKD and HD are positively associated with suicide.
  • Suicide is preventable through early identification and management of mental and physical health issues.
  • Physicians should assess mental and physical disorders, especially in early-stage HD patients.